The FDA Has Approved An Obesity Drug That Helped Some People Drop Weight By 15% – NPR

This image provided by Novo Nordisk reveals a bundle of the companys semaglutide medication, named Wegovy. On Friday, the FDA said this new version of a popular diabetes medication could be offered as a weight-loss drug.

Cristian Mihaila/AP

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Cristian Mihaila/AP

This image offered by Novo Nordisk shows a bundle of the companys semaglutide medication, called Wegovy. On Friday, the FDA said this new version of a popular diabetes medicine could be offered as a weight-loss drug.

Cristian Mihaila/AP

Bays said Wegovy appears far safer than earlier obesity drugs that “have actually gone down in flames” over security problems. Wegovys most typical adverse effects were intestinal problems, consisting of vomiting, diarrhea and nausea. Those usually decreased, however led about 5% of research study individuals to stop taking it. The drug carries a prospective risk for a type of thyroid growth, so it shouldnt be taken by people with a personal or family history of specific thyroid and endocrine growths. Wegovy also has a risk of anxiety and pancreas swelling. Wegovy (pronounced wee-GOH-vee) is a synthesized version of a gut hormonal agent that curbs appetite. Patients inject it weekly under their skin. Like other weight-loss drugs, its to be used together with workout, a healthy diet plan and other steps like keeping a food journal. The Danish company hasnt disclosed Wegovys cost however stated it will resemble the price of Saxenda, an 11-year-old weight reduction drug injected daily that now generally costs more than $1,300 monthly without insurance. Dr. Archana Sudhu, head of the diabetes program at Houston Methodist Hospital, stated Wegovys usefulness “all depends upon what the rate will be.” She noted patients medical insurance prepares sometime do not cover weight-loss treatments, putting expensive drugs out of reach.

Sudhu, who has no connection to Novo Nordisk, plans to switch patients who are obese and have Type 2 diabetes to Wegovy. Wegovy builds on a pattern in which makers of reasonably new diabetes drugs check them to deal with other conditions common in diabetics. She stated she got Wegovy, worked out several times a week and lost 65 pounds over 16 months.

The Food and Drug Administration approved Wegovy, a higher-dose version of Novo Nordisks diabetes drug semaglutide, for long-lasting weight management. Bays said Wegovy appears far more secure than earlier weight problems drugs that “have actually gone down in flames” over safety problems. The Danish company hasnt divulged Wegovys cost however said it will be similar to the rate of Saxenda, an 11-year-old weight loss drug injected daily that now usually costs more than $1,300 per month without insurance coverage. Wegovy constructs on a trend in which makers of reasonably new diabetes drugs evaluate them to deal with other conditions common in diabetics. She said she got Wegovy, worked out numerous times a week and lost 65 pounds over 16 months.

Regulators on Friday stated a brand-new variation of a popular diabetes medicine might be sold as a weight-loss drug in the U.S. The Food and Drug Administration authorized Wegovy, a higher-dose variation of Novo Nordisks diabetes drug semaglutide, for long-lasting weight management. In company-funded studies, participants taking Wegovy had typical weight-loss of 15%, about 34 pounds (15.3 kgs). Individuals dropped weight gradually for 16 months prior to plateauing. In a comparison group getting dummy shots, the typical weight-loss was about 2.5%, or just under 6 pounds. “With existing drugs, youre going to get possibly 5% to 10% weight reduction, often not even that,” said Dr. Harold Bays, medical director of the Louisville Metabolic and Atherosclerosis Research. Bays, who is also the Obesity Medicine Associations primary science officer, assisted run research studies of the drug. In the U.S., more than 100 million grownups– about 1 in 3– are overweight. Dropping even 5% of ones weight can bring health benefits, such as enhanced energy, blood pressure, blood sugar level and cholesterol levels, however that amount typically doesnt satisfy clients who are concentrated on weight loss, Bays said.