Have scientists found the key to beating prostate cancer? – Daily Mail

Prostate cancer cells are seen aboveNow, researchers at the Institute of Cancer Research (ICR) and the Royal Marsden Hospital in London say they have actually got the response– and it is a protein called CD38.The cancer hijacks white blood cells called B-cells and controls them to make CD38.Research suggests it then deprives other cancer-killing white blood cells of the energy they require to assault the tumour.This implies that drugs that target CD38 could unleash the power of the immune system on the cancer cells.Crucially, such medicines currently exist and trials are underway. Research recommends it then denies other cancer-killing white blood cells of the energy they require to attack the tumourGiven to 24 males with advanced prostate cancer, isatuximab– an immunotherapy used to treat blood cancer– re-energised the cancer-killing white blood cells, a conference heard last month.Researcher Professor Johann de Bono stated: Theres a lot of proof that prostate cancer triggers what we call immune tolerance– that the cancer reduces the body from attacking it with its immune cells. Samples from more than 200 guys with innovative prostate cancer exposed that those whose tumours had a lot of CD38 protein were twice as likely to pass away in the next 10 to 15 years.The research, released in the journal European Urology, likewise discovered that the cancer became harder to deal with as levels of the protein rose.Prostate cancer is the most common cancer in males– with 48,500 cases a year and almost 12,000 needless deaths.

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